ALLERGEN-SPECIFIC IMMUNOTHERAPY WITH LIPOSOME CONTAINING CPG-ODN IN MURINE MODEL OF ASTHMA RELIES ON MYD88 SIGNALING IN DENDRITIC CELLS

Allergen-Specific Immunotherapy With Liposome Containing CpG-ODN in Murine Model of Asthma Relies on MyD88 Signaling in Dendritic Cells

Changing the immune responses to allergens is the cornerstone of allergen immunotherapy.Allergen-specific immunotherapy that consists of repeated administration of increasing doses of allergen extract is potentially curative.The major inconveniences of allergen-specific immunotherapy include failure to modify immune responses, long-term treatment l

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Bone Regeneration: Mini-Review and Appealing Perspectives

Bone is a natural mineral-organic nanocomposite protecting internal organs and allowing mobility.Through the ages, numerous strategies have been developed for repairing bone defects and fixing fractures.Several generations of bone repair biomaterials have been proposed, either based on metals, ceramics, glasses, or polymers, depending on the clinic

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Clinical impact of diabetes mellitus on 2-year clinical outcomes following PCI with second-generation drug-eluting stents; Landmark analysis findings from patient registry: Pooled analysis of the Korean multicenter drug-eluting stent registry.

BackgroundPatients with diabetes mellitus are at an increased risk for adverse clinical events following percutaneous coronary interventions (PCI).However, the clinical impact of diabetes mellitus (DM) on second-generation drug-eluting stent (DES) implantation is not well-known.The aim of the current analysis was to examine the clinical impact of D

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Population genomics and demographic modeling enhance our understanding of trophic level interactions in biological control

In this paper, we focus on the application of population genomics, including next-generation sequencing and demographic modeling, to enhance the understanding of historical and contemporary trophic level interactions that are a fundamental basis of biological control.We outline how the integration of ecological approaches with population genomics a

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Seismic motion input methods of viscous-elastic boundary and numerical simulation of seismic response on large diameter tunnels

To determine the selection of input wave field at the bottom of the viscous-elastic boundary, and study the seismic response of two parallel large-diameter shield tunnels, corresponding numerical models were established for analysis.First, through the study blueberry bubblicious of wave method for seismic motion input of viscous-elastic boundary, s

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